General rules for functional microRNA targeting
نویسندگان
چکیده
منابع مشابه
Rules for functional microRNA targeting
MicroRNAs (miRNAs) are ∼22nt-long single-stranded RNA molecules that form a RNA-induced silencing complex with Argonaute (AGO) protein to post-transcriptionally downregulate their target messenger RNAs (mRNAs). To understand the regulatory mechanisms of miRNA, discovering the underlying functional rules for how miRNAs recognize and repress their target mRNAs is of utmost importance. To determin...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2016
ISSN: 1061-4036,1546-1718
DOI: 10.1038/ng.3694